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Multivariate pattern recognition studies should be carried out in order to (a) define clinical subtypes of ME/CFS and chronic fatigue and their associations with co-occurrent depression, and (b) examine the shared IO&NS pathways versus those that discriminate both disorders

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de Souza JA, Vindis C, Negre-Salvayre A, Rye KA, Couturier M, Therond P, Chantepie S, Salvayre R, Chapman MJ, Kontush A

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